Yep. I have done it more than I want to admit. About 5 years ago I got interrupted by a phone call while getting ready to head out on the road. I had just filled up my travel humidor and was in a hurry to get to the airport. I ended up heading out the door and left the lid of my coolidor open in the process. Five days later I returned to an open coolidor and the panic set in. Thankfully everything was OK but I was MUCH more careful after that.
This is actually one of the main reasons I got my Sensor Push hygrometers. The app sends me a message when the humidity gets below the level I set up as my "bottom". This has saved me more than a little anxiety over the past couple years.
I did it one night whilst having many cocktails. I came down stairs the next morning and you could smell it halfway down the steps. Sometimes I feel that I don't get that whoosh of cedar and cigars upon opening as much anymore.