Absolutely. Some aromatics are heavily dowsed with PG (propylene glycol) to preserve their moisture - same stuff as is in some passive humidification devices in humidors. It's present in many types of tobacco, but seems to show up in bigger amounts in aromatics and "drugstore" tobaccos. This can gather in the heel of the bowl as you smoke and create the gurgle.
The physics involved in the airflow down a bowl and through the shank/stem/bit are also a little more complex than you'd think. Offset drilling creates more turbulence, and large, open areas within the pipe (i.e. the space where a filter would go that doesn't have a filter in it, or a tenon cut too short) will create a plenum in there where the smokestream will expand/contract and condense moisture out. This can then also gather in the bowl. This moisture can subsequently heat up and add steam to your smoke, which will help with the chemical goings-on that create what we know as tongue-bite. Not fun. If you're a little handy and have a rat-tail file you can mess around with the openings and try to line them up/size them up to be as smooth a flow as possible - kind of like porting an engine in micro-scale. If the drilling is at least close to correct, the pipecleaner down the stem can also help keep it dry.
The other thing that can influence this is a draught hole that enters the bowl too high - any tobacco below the hole won't burn, and small pieces can slide into the airway and wheeze or gurgle if it gets too wet.