I have Norton on my desktop and Mcafee on my laptop. I prefer Norton partly out of familiarity but mostly due to the fact that it recently took me several months to get a Mcafee update that I paid for to download to my laptop. Their customer support sucked wind. The FAQ's they kept refering me to were useless and the online support rep that I finally got hooked up with didn't have a clue as to why it wasn't working. I wound up having to call their pay-per minute service line twice. The first time I called they were baffled and were supposed to call me back and never did. I had to call them again and both times I spent most of the time on hold while the meter ran (at like $3.00 per minute). It cost me around $80 to get the update to work after paying something like $30 for the update itself. Never again.
I'm using AVG at work and on the Laptop. I like it better than any I've used before. Easiest system I've ever seen. Too bad they stopped offering it for free recently...